منابع مشابه
TCAF1 puts a chill on prostate cancer
TCAF1 puts a chill on prostate cancer The partner of a cold-sensing ion channel prevents prostate cancer cells from migrating, Gkika et al. reveal. The ion channel TRPM8 detects low temperatures, but it occurs in parts of the body that aren’t exposed to the cold, such as the prostate and bladder, suggesting that it has other roles. The protein is overexpressed in prostate tumors and other cance...
متن کاملTRPM8 Puts the Chill on Prostate Cancer
Prostate cancer (PCa) is one of the most frequently diagnosed cancers in developed countries. Several studies suggest that variations in calcium homeostasis are involved in carcinogenesis. Interestingly, (Transient Receptor Potential Melastatin member 8) TRPM8 calcium permeable channel expression is differentially regulated during prostate carcinogenesis, thereby suggesting a potential function...
متن کاملAdvertising campaign puts face on prostate cancer.
Meet Prosty the Spokesgland. The plucky prostate recently debuted on Capitol Hill, starring in a television advertisement designed to rally support for research into effective imaging tests for prostate cancer. “ Women have the mammogram, ” said Faina Shtern, M.D., president and chief executive offi cer of the nonprofi t AdMeTech Foundation, which organized the October press event. “ Men want t...
متن کاملRHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy
PURPOSE The lack of biomarkers that can distinguish aggressive from indolent prostate cancer has caused substantial overtreatment of clinically insignificant disease. Here, by genome-wide DNA methylome profiling, we sought to identify new biomarkers to improve the accuracy of prostate cancer diagnosis and prognosis. EXPERIMENTAL DESIGN Eight novel candidate markers, COL4A6, CYBA, TCAF1 (FAM11...
متن کاملAssociation between prostate specific antigen change over time and prostate cancer recurrence risk: a joint model
Background: Prostate specific antigen (PSA) is an important biomarker to monitor patients after treated with radiation therapy (RT). The aim of this study is to evaluate the relationship between the PSA data and prostate cancer recurrence using the joint modeling. Methods: This historical cohort study was performed on 422 prostate cancer patients. Inclusion criteria included: patients with loc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2015
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.2081iti1